My old raiding main is a Rogue, so I've been dragging him through since BC on various teams... (I can't bring myself to level a toon solo anymore... just seems so wasteful! So I've cobbled together a couple different approaches, none of them ideal for multiboxing, but I've managed to get passable DPS out of him, but still about 2/3 of what I can get on casters or other melee classes.

"Best" approach I found was to use ISBoxer to create a clickable video feeds window into the rogue window that shows a couple buttons and his combo points bar and then drop the finishing moves in there... put Sinister Strike on my spam button and then just manually click the finishing moves when combo points get to 4 or 5. Combine that with the Melee Interact with target mechanism and its acceptable.

Generally I love playing the rogue solo for questing and some max level stuff, but having him on a team for anything but the most basic leveling has just been painful...