To clarify, you would spam your hotkey... not press it just once.

Each 0 in the macro, is the equivalent of "do nothing on this press".
By staggering the 0's, in a variety of castsequences, you're staggering when key abilities might fire off.

With a macro of this type, you'll basically need to tweak it for your spam speed, of your DPS hotkey.
Either that, or adjust your personal spam speed.

In the past, Blizzard has removed the ability for a one button spammed macro to work.
So don't be surprised if in a major content patch, or next expansion (whenever that is), is this type of macro breaks.
It used to be ,,,,, with nothing happening on each of the commas; the 0 is essentially an item slot, which doesn't have a click/use effect; Blizzard removes something, others find a work-about, back and forth the game goes.