Have you read the Newbie's Guides sticked at the top of this forum or the Jamba Guide stickied in the Macros forum?

http://www.dual-boxing.com/threads/3...to-Multiboxing
http://www.dual-boxing.com/threads/4...tiboxing-Vol-2
http://www.dual-boxing.com/threads/2...etting-Started

The first link has loads of guides for setting up ISBoxer, including several video tutorials.