I don't see why not.
I have done quite a few and im not even geared out.
(5pally team) 1prot/4ret.
right when i dinged 80 i cleared Culling of Strath as a random no problemo.
i think the hard ones are HoL (3rd boss)... forge of souls 2nd boss... ToC 1rst boss with rogue..and idk i haven't gotten to deep into it.
some snags were i know it can be done with a healer but hope gear will fix it.