I used to spec frost when tanking on my DK/4Ret team.
After having switched to Blood for my guilds ICC runs i started using Blood in my box setup too.... Amazed at how effective it has become.
As a Blood tank i use 2 macro's.... only 2.
Both Castsequence macro's starting with /startattack and ending with /cast !Rune Strike.
SingleTarget:
/castsequence reset=4/combat Icy Touch, Plague Strike, Death Strike, Heart Strike, Pestilence, Death Strike, Heart Strike, Heart Strike, Heart Strike, Heart Strike.
This is done with the talent Death Rune Mastery turning the FU runes from death strikes into Death Runes. So the rotation looks like:
F(rost), U(nholy), B(lood), D(eath)
F, U, FU, B, B, FU, D, D, B, B, repeat
This allows for massive single target treath especially with the new threatbuff to icy touch.
I use this to singletarget tank stuff like saurfang or rotface/festergut (or any ICC boss actually)
For AoE i use a 2nd macro.
/castsequence reset=4/combat Icy Touch, Plague Strike, Pestilence, Blood Boil, Death Strike, Death Strike, Heart Strike, Pestilence, Hearth Strike, Heart Strike, Death Strike, (repeat from 1st pestilance, copy/paste 10 times in Super Duper Macro addon)
This looks like:
F. U. B, B, FU, B, B, D, D, FU. (repeat)
I usually cast 1x DnD up front for extra aoe agro to start with, sometimes followed with an extra DnD halfway if new add's spawn. Adding a DnD up front using up FUB runes, leaves enough runes for a disease/pestilence start followup with a short wait till it BloodBoils. No 10k dps mage pulls agro off of me
Thanks to the /cast !Rune Strike and being a tank (ie. getting hit a lot) means i dont have to use up runepower for deathcoils or anything. My runepower is usually between 20 en 70 the entire fight, I hardly never top it or deplete it completely, always having enough extra to use for CD's
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