Yeah every now and then I have one of those nights. I just wipe on stupid stuff, all my macros seem to break and I want to smash my computer and quit the game. Thats when I know I've been playing too much WoW.

I have other nights where I can do no wrong, my slaves all do 6k+ DPS on bosses and I smash everything I touch seamlessly and easily.

I really do think that whether you feel it or not, multiboxing is very tiring and draining. You are concentrating on so much more - I think things like /click macros have helped take some of that strain off but still you are worrying about 5 characters not just 1.

And having kids is the reason I came back to multiboxing - I can AFK at any point of an instance for however long I want. I have afk'd in things like Halls Of Lightning or Pit of Saron for like an hour as I keep needing to do other things.

DK + Rets seems really fun - I wish I had it in me to level another team - perhaps for Cataclysm I will do this? Not sure.