I am running the X-keys Pro with Win7 on problem. The good thing about the X-keys is you can always go hardware mode allowing you to use it where ever you want.

all the video issues should be no problem. I have not tried assigning a particular video card to an application though.

If it was me I would install everything on RAID 0. I am not sure what the performance gain or loss would be seperating the OS on the SATA and WoW on the Raid. I would like both applications to take advantage of RAID if I could.

either way Win7 is a great upgrade from Vista. The only isues I had were some problems with ACPI driver and power management in general but both were cleared up easily. If you have any issues they will most likley be related to drivers.