Alright I'll try and narrow this down even further.

CPU = Quad Core Q6700
Graphics Card = ATI Radeon 4870 512MB
RAM = 8 Gigs
2X500GB SATA 7200RPM Harddrives

I use two folders for WOW one for my main and one on my other drive for the 4 slaves. I have Symlinked the Cache and Data folder from the slaves to the main folder and use no addons whatsoever.

As for my main graphic settings I have it all set to max and use a resolution of 1680X1050 on a 22' inch screen, Maximizer in keyclone is set to 1440X1050. As for my slaves they are set to the lowest graphic settings with nothing on just sound. They are split on a 17 inch monitor that the resolution is set 1280X1024 and in keyclone they are set to 640X512 split into 4 even boxes, but in the maximizer I have them set to 1440X1050.

I've done the tcpackfrequency edit, so I'm not sure what else you would need me to list.