One of the first key bindings that I change is Num_lock. I could never understand why Blizzard made it the default key for run. Nothing like having Number Key Pad bindings not work when you least expect it ;)

I do not have so much of an issue or toons running off without me but rather the other way around. I have a bad habit of being half way across the world and forgetting one poor toon somewhere. I expect social services to call me any minute.