Any tips to play mixed casters effectively?

[Apatheist]

#showtooltip
/use [@target,harm] Moonfire;[@mouseover,help] Rejuvenation

I find combining multiple offensive and defensive skills into a single keybind helps a lot.

#showtooltip
/castsequence reset=3/target Curse of Agony, Corruption, !Shoot,,,,,

It used to be possible to create a false cooldown with castsequences using commas that can help a lot in managing multiple DoT's. I'm not familiar with the new API so somebody else will have to confirm whether something similar is possible currently.

[MiRai]

It used to be possible to create a false cooldown with castsequences using commas that can help a lot in managing multiple DoT's. I'm not familiar with the new API so somebody else will have to confirm whether something similar is possible currently.

The ability to do that is long gone.