I currently use a 4K 42" UHD420 display.
In my opinion, I think 1080p stops looking acceptable after ~27" where the pixels reach the point where they can become noticeable, which can affects image crispness.
It's hard to say because it's subjective—some people swear by using multiple displays—but after switching to a single large display, I certainly enjoy using a single large display for everything.
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