Different Resolutions

[MiRai]

I don't see why not... assuming your computer can handle it.

I just ran 5 clients at 3240 x 1920 last week as a test on SLI'd 580's yet the performance was less than I would
have liked.

EDIT: I guess I could elaborate a bit more. The performance wasn't that great because my GPUs were pegged
at 100% the entire time and had nothing to do with ISBoxer. After a while of playing in surround, the monitor
bezels just begin to remind me why I game on a single monitor and I would much rather just buy a nice 30"
and play on that. Also, with your different resolutions you won't be able to utilize 1:1 mouse broadcasting nor
will you be able to use instant swapping.