Macros and addons cannot make decisions for you, so no.
Null is a non-existant spell. It is used to force a macro to lock up. The same can be done with Nil, Frank, Supercalifragilisticexpialidocious. Since there is no spell by that name, the macro can progress no further. It is used when you only want to cast a spell or sequence once, such as Hunter's Mark or Curse of Elements, and is usually in a macro with a reset conditional.
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