You can't compare ISboxer and jamba.
Jamba helps you ingame and does not control what keys get send to wow's.
Personally i bound the heals on my restodruid to seperate keys and only broadcasted those to the druid, with Isboxer. Since i hardly used alt as a modifier, i bound heals to keys with alt as a modifier, works great for me.
Most people use Repeater regions. Something like this should explain the idea:
http://www.dual-boxing.com/showthread.php?t=30511
Depends a bit on the aim you have. PVE or PVP. I need my mouse for targetting in PVP, so can't use it to click my healtargets. In pve, this should be no problem.
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