With Grid, the best sorting options will require also having GridCustomLayouts.

The two main sorts I use are:

/Grid Config
Click on Layouts.
Click on Custom Layouts.
Click on New.

Entering: " order=NAME; " (without the quotes, will get you an alphabetical listing).
Entering: " nameList="ToonA,ToonB,ToonC,ToonD,ToonE" " (without the outside quotes, will get you a static listing of those toons and no one else).



On the addons used thread, on the isboxer.com forums, one guy mentioned he is using both Grid (+GridCustomLayouts) and Vuhdo for his team.

Basically has one set of unit frames configured to do certain things on clicks.
And the other unit frame does different actions on clicks.
I've not gone this route, but thought it was a neat idea.

You can also have your repeater region covering only the left or right half of the bars (assuming vertical layout), which can allow for Cleanse from the tank if you click the left half, or a click passed to the healer if you click the right half.

A lot of options.