You shouldn't have to click the mouse at all, the interact with mouseover key should do whatever action is appropriate. My interact with mouseover key is `. I stack my guys up, move my mouse over the node or whatever and hit `, and that's all.

You keep saying that it works if you're in range. You have to be in range to use it. If you aren't close enough that you couldn't - for example - mine a node on your main, then you won't be close enough for your slaves to do it.

Your mouseover area will also need to be free from obstruction as well. For instance, my team has 2 shamans on it, which means I usually have Water shield, Earth Shield and Lightning Shield swirling around me when I'm stacked up. If those shields get in the way when I'm interacting, then they are trying to click on the shields, not the node, or if I'm standing on top of a node, they might end up trying to interact with someone's foot instead.