If you have the time to look into it, I would really recommend Octopus. I use version 1.3 and it works great. It works fine on a single box (you don't "HAVE" to have multiple boxes). You can set it up to the point where it will open each window on the correct screen, ready to go (full sized, or custom sized). I even have it configured so that each toon runs on their own processor, and when WoW launches it has the correct toon selected. You can disable mouse broadcasting if you want - but I love it for selecting the FP/Quest givers on both screens at the same time. I also use MBV2- great little app.
A note about Octopus - set it to Blacklist at first, and only broadcast specific keys to your alt. It is easier that way when you have established toons.
For addons, I would HIGHLY suggest getting Trinity Bars 2.0 - the ability to set buttons to type "Macro" means they are not stored server side - so that when you want to take your pally raiding again you don't have to re-arrange all your bars.
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