Yeah, it's tough to adjust. For fear bombs, that's a bitch unless you keep tremor totems down.

Regarding AoE, bind a key to do self-targeted chain heals and things become a LOT easier.

My follow button for my alts is the same button I use to "move forward" on my main, so it's very natural to just "bump move" forward to refollow alts.

Regarding assists, all my guys work off of /assist focus (my main is focus) and keep in mind that you can still target people while dead. I also have separate keys bound to be able to turn my alts all at once regardless of /follow. (WASD is my main ONLY movement keys. My L/R/U/D arrow keys move everyone independently).

Regarding heals, I have 8 keys setup for this. 1-5 cast Lesser Healing Wave depending on which one I see needs healing (/cast [target=dondiego] lesser healing wave). My 6th key casts lesser healing wave on whoever my focus target has targeted (focustargettarget). My 7th key casts max rank Healing Wave on a fall-through macro. My 8th key has Chain Heal cast on Self(/cast [target=player] chain heal).

Adjust to taste. It isn't easy or obvious at times, but you'll get used to it after a bit.