Thanks for the feedback/comments everyone.

I ended up starting with:
1 x Dwarf Paladin
1 x Dwarf Priest
1 x Gnome Mage
1 x Gnome Warlock

I'll bring the Druid on a little later after these 4 are lvl 15 or so as i'll solo up the druid to meet up with them outside the starter zones.

It was a helluva learning curve just starting and getting the macros complete at low levels...and there aren't many spells to manage at this point. I'm sure as I get up in lvls and have more options it'll become a near nightmare. I assume everyone goes through that part though just figuring out setting focus for all toons, key bypasses, round robin, formations, etc. Also I still go to each window using multiplicity for quest acceptance or to loot so it is definitely a little slower.

REGARDLESS - I actually like the challenge this provides. I was drifting away from WoW but this has gotten me interested again (curse of goodness).