well.. you could use the mouse-click-passing (mcp) to make dealing with the quest givers a bit easier.

basically, go to keyclone/setup/general and set your mcp hotkey (i use F4, since i'm not using it for anything)

then, once in the game and standing in front of a quest giver (QG)...
i right click the QG on each wow (5 clicks)
then i toggle mcp on (F4)
then left click the QG menu.. DO NOT MOVE MOUSE while it bounces screen to screen clicking the button
repeat until you're finished
then toggle mcp off (F4) <-- don't forget

so, if you have to turn in a quest and accept another... that would typically be at least 'complete/accept' .. or 2 clicks per wow (10 clicks total). with mcp, it's just 2 clicks

i hope that makes sense.