LOL - actually what the hell, 3rd edit, Ill rephrase my question to be absolutely sure...

As I understand it, you could use one graphics card to power two monitors and then use Vistas span mode to create one big desktop resolution which you would then turn into regions with Maximiser. In my example, I would have the main running on the left monitor in full-screen and the second monitor would contain the four slaves split equally into squares.

Will an 1024MB 8800GT handle that load adequately (It looks like the max resolution wouldnt allow me to keep each screen at 1280 x 1024) or is it better/easier/more efficient to just get 2 x 512MB 8800s and have them each power one monitor?

Am I making sense?