Quote Originally Posted by 'Fursphere',index.php?page=Thread&postID=81196#pos t81196
But like in D2, there were six quests per zone, and you had to do them in order to progress.
A1- everything skippable except the act boss.
A2- the first quest is skippable, but you did need to get the 3 parts, although you get to keep the cube for nightmare/hell. Summoner is required, but is along the way.
A3- Just need to get the flail parts, everything else is skippable.
A4- Just need boss.
A5- The ancients are required, but are on the way there. Everything else is skippable.

This is without help. I don't remember the exact restrictions that were added, but long ago you could take a portal to the act boss's room, have them killed, then go right to the next act. This doesn't work anymore.

I imagine the quests will be similar, they will either have rewards that you want to get(permanent boost) or are required to get to the next area. A mix of both most likely. EXP rewards aren't out of the question which could mean more skipables that don't have otherwise good rewards.