I've got skinning on my main and I intend to get enchanting on another just to disenchant items that I can't use.

Ive got all 5 on the go at the moment, running round Westfall trying to get the knack of it.

I reckon I need another pair of hands, not sure if I'm doing it at all right.

I've got the numlock 1-5 for my mages spells and ctrl 1-5 for healing the party members and then normal numbers for my mains abilities. With macros for targeting and following.