I use a Lachesis and N52. You don't really need to click anything with those for combat and most things.

Think you just need to set your N52, then your keybindings to that. I have mine so that tab is top left, alt under it, ctrl, under that, and shift is to the right of it. movement is as it was, and 1 to = are around those including the nintendo style toggle. I use Bartender to set up my rows, and keybind WOW to those. So on my shammy regular spells are 1,2,3 up to =, etc and totems are Alt 1,2,3...=, less often are ctrl 1,2,3...=

Do the same for the mouse, keybind like KS to mousebutton 5, and blind to Alt mousebutton 5. My hands never move only fingers. With all the combinations you can easily put your trinket on something. Forget clicking even without dual boxing. Now keyclone does what you need.

Hope that made sense.