I run around with 5 boxing on: E6600 (dual core), 8800gt, and 2gb of ram, I have to say the only thing cockblocking me is probably the ram, it maxes out at 100% usage with 5 up, I could probably do with just 3gb and it would be enough. And I only really notice a chug when I am in a densely populated area, otherwise its about 85% usage