Quote Originally Posted by 'moosejaw',index.php?page=Thread&postID=75750#post 75750
May I add that if your "focus doesn't follow mouse", then just hovering your mouse on the screen will highlight the object but to interact you must "select" the screen first. Thus 2 mouse clicks to loot instead of a hover and keyboard press.

So the difference is Hover and keyboard -or- 2 mouse clicks. Basically less stress for your clicking fingers.
I've been clicking twice on each window and looting - the "focus follows mouse" will save a load of time.

I'll have to try the original posters suggestion as well.