What I ended up doing when I wanted multiple Keyclone maximizer setups is to just enter the details of the new setup under new names without interfering old one.. for example I have zones TopLeft, TopRight, BottomLeft and BottomRight for when I've running a 2x2 display but now also have Top and Bottom for when I've got a couple of guildmates along and so just want to display two characters on that screen.

This does 'hide' the first set behind the second but to be honest it's only going to be an issue should I get a different monitor with a higher res.