What is the best way to do this?

I've been looking at using this motherboard.
http://www.asus.com.tw/products.aspx...14&modelmenu=2

Two of these:
http://www.asus.com.tw/products.aspx...01&modelmenu=2

8Gb ddr, vista 64-bit, rest doesn't matter much.

But I have no experience running more then one videocard in one pc. Is it feasable to run a quad set up with four monitors with this hardware?