You may want to try the following to control your WoW client Layouts:
https://wowopenbox.org/
Even if you only use it for layouts it is worth it (though it does a lot more). The following is an example of what the Layout Wizard looks like on/for a 4K monitor used as a 2nd monitor in a multi-monitor setup:
https://wowopenbox.org/sshotWindowLayout.png
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