I was running all 5, leveling in starting zones from level 1. Then once I hit barrens, I got a whisper from someone saying they'd "report unless I gave them gold." I'm now switching to 2 boxing until I can start grinding dungeons. From there, I'll level 100% through dungeons until outlands, then grab some quest greens to get ready for Ramparts. I use window resizes and ease-of-use mouse over, but if bans are happening based on reports - its just not worth playing out in the open for me.