On Defiant I am running Paladin/Void Warrior Tank, 2 Pyro Mages, Chloromancer and Bard for support. My Guardian team swaps the Warrior for a Cleric tank. The Cleric seems to have an easier time with aggro. I have the Pyro Mages set up with an additional Stormcaller role to clear AoE.

Macros in Rift have a fall through mechanism so if you put your longer recast items near the top and an instant cast at the bottom you can get a decent rotation from that.