I do a hybrid. I have 3 main DPS keys, and all the DPS and tanks have the same GSE macro on all 3 keys. The healer has three options, one key is for DPS, another for passive heals, and the third does nothing, and I utilize click healing through clique, to a Grid2 window, with a repeater region overlay, so I can heal from any screen.

It needs work, as I'm often overhealing and running OOM quickly, but it's a starting point.