LoL I hadn't though of Ice Block to bypass mechanics and you could do it at least twice on a given boss by leveraging cold snap. If you have Paladin Healers they can also be immune to any mechanic at least once (maybe twice depending on the mechanic). Those are without popping any invul pots.
Warlocks could sacrifice Voids to get a really big buffer which may allow quite a bit but I can't think of a way for them to be totally immune like Mages or Paladins.
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