You gave me a reason to do a bit of research. I was trying to figure out how I could use the keymaps most effectively. I have the first keymap 1-= for the 1-14 keys and that is all I have needed so far. Now that I have reached level 40 I am staring to run out of keys on the n52te even with modifiers. I have yet to use the scroll button for anything, so i plan to use it to toggle keymaps. I'm still stuck on what keys to bind for the other keymaps. I only use the fkeys for target leader and focus. I might go ahead and move that function into a macro and use the fkeys.

I found this thread that has a bit about keymaps for wow.
http://www.n52te.com/community/index.php?showtopic=253

If you are still having trouble ask for help here:
http://www.n52te.com/community/index.php

I'm still a nub with my n52te.