Any ISBoxer user can do this on one PC with mouse broadcasting and tell you how it will work out.

As I understand Runescape, your character moves between tiles in the game world. The precision of your clicks to move in Runescape is therefore completely different than with WoW. All you have to do in Runescape is click on the same tile.

I don't think you're going to have any more luck keeping your characters together with Click to Move in WoW than holding W. The amount of clicking you're going to be doing, and the precision of those clicks, is going to prevent that from working out. Each click you do will spread your team further apart.