I would do a bit of review research on that motherboard with M.2 NVMe drives. I've had two motherboards (one MSI, one Asus) in the last few years that experienced some I/O stalls with two of those drives in RAID 0 but had no issues with normal SATA SSDs. The user experience was basically some relatively "bursty" performance that resulted in some stuttering in games that do a lot of dynamic texture loading (like WoW when zoning into a big capital city). Might have just been early-adopter syndrome but I figured it would be worth mentioning.