Thank you for your response and I'm sorry if other info was needed. I thought what I gave was sufficient to answer for two variables in generic situations.
I have an Intel I7 8700 on an Asus Rog board with 32gigs of ddr4 3200mhz ram. Operating system and WoW are both on a Samsung 970 vnand ssd. I was waiting for video card prices to drop but seems it isn't happening. Currently, until I get the 2070 I just ordered, I'm running a 1060 3g for the primary and 1050ti for the secondary. Both monitors are HDMI 1080p 60hertz native. My primary monitor is 32" and secondary 22". I set Isboxer settings for 30 frames in front and 15 in background. The settings I use allow me to play smoothly using Directx11. The graphics slider is set at 2 then the slot swap tweaks it from there, and 1080 whatever is the resolution. Here's my slot swap macro.
LOW SETTINGS
/console graphicsQuality 2
/console graphicsViewDistance 2
/console graphicsEnvironmentDetail 2
/console graphicsGroundClutter 1
/console graphicsShadowQuality 2
/console graphicsLiquidDetail 1
/console graphicsParticleDensity 1
/console graphicsTextureFiltering 3
/console RenderScale 0.5

HIGH SETTINGS
/console graphicsViewDistance 7
/console graphicsEnvironmentDetail 7
/console graphicsGroundClutter 2
/console graphicsShadowQuality 3
/console graphicsLiquidDetail 2
/console graphicsParticleDensity 3
/console graphicsTextureFiltering 5
/console RenderScale 1.0