Well, for looting you can use Interact With Target, which is essentially a key bound click on your current target. You can find it under "targetting" in your ingame keybinds.

As far as quest dialog, flightpaths, etc. I recommend using the Jamba add on. It'll allow your slave toon to follow the choises you make on your lead character in NPC dialog boxes. It has a metric ton of other quality of life functionality for boxers as well. It might look overwhelming at first, but it's actually fairly logically set up and categorized.