Still having the problem. Been trying to troubleshoot it. Pretty sure that out of the box with new ISboxer 42, for some reason it is not activing the Quick Setup 42 Macro Sets. This is under Game Helpers --> World of Warcraft --> Macro Sets --> Quick Setup 42

Been slammed at work and haven't been able to spend a lot more time with it. I have tried the wizard quick setups, regular and pro. Still have the same issue.

Also, I was able to manual activate Jamba from wow through just the command line.
It just seems that all the Quick Setup 42 macros are not being enabled at startup or even on swapping of screens (assist, focus, click to move, jamba, etc).

Any Ideas?