Ugh, I can't figure this one out.

[mbox_bob]

I think this might be a clue. When your leader targets the last target you had, it usually means you are sending the /assist {FTL} to everyone and not "all other" so your main is re-targeting again pointlessly. There could also be some unexpected interaction with "sticky targeting" in the wow ui options as well.

No. As I explained above, that particular issue was caused because I had him change the Key Combo on the Assist macro to something other than BACKSPACE. He choose [, which is normally assigned to /targetexact macro. He exported, but did not to a /console reloadui, so ISBoxer then sent FTL+[, which the prior ISBoxer Addon registered as /targetexact, so everyone targeted the main. After doing a /console reloadui to load the new ISBoxer Addon, back to the behaviour of no assist.

Typing in /assist CHARNAME on the in game console should work. It is not. This is the issue. /assist CHARNAME does nothing in game (nor /a ).

[Multibocks]

It was an in game issue that a developer fixed for me by taking my account for an evening. No idea what they did, but it fixed it!

[Ughmahedhurtz]

Was that account a trial at one point? Aren't trial accounts restricted from certain things?