I definitely have the focus mouse option enabled (I didn't see the option, but I did wonder why I was focusing on windows without clicking on them 8o ) so I'll disable that when I get home and see if that helps.

Would setting the monitors to horizontal span rather than dual view help? I don't really want to (another solution = better!), but the mouse is driving me insane!

Regarding the PiP issue with cutting off the bottom of the screen, I still haven't got that to work correctly. Sometimes when I switch it will resize correctly with no problems, but then I'll switch again a minute or two later and the main region on left monitor cuts off at the bottom, hiding one of my bars and the bags etc. and the only way to fix it is to completely exit the game, and reload. I've checked that the regions are the correct size in the maximiser settings so I'm not sure what's causing it. Possibly my Vista doing it's own thing as usual? :thumbdown: