My isb profile is not really interesting since it's using the "pro" system which means there's nothing in isboxer besides virtual key maps that do nothing. I use gs-e and that's where all the macros are.
During WoD I played with gs macros + isb and used the macro keys on the g710+ to repeat the key presses every 50ms or so. worked fine... not sure if it was super optimized, but in tanaan things melted.