How to Handle Macros Leveling Up?

[Teknetron]

I think Mirai uses a great advanced system. You should def. watch his videos.
With his system I believe you can drop in any character into any team.

I myself just use what I've been using since I started using IsBoxer years ago, I'm one of those types that when something works for me I just stick with it lol

In IsBoxer I usually create new key maps for my classes.
So I would create the following key maps for my current group.
AlwaysOn - Always On Macros
Combat - Combat Macros (not class specific, more like Q = everyone attack, E = Pull Attack)
General - Movement Macros, Quality of Life Macros
Paladin - Class Macros
Hunters(3) - Class Macros
Priest - Class Macros

Paladin will use KEYPAD
Hunters will use SHIFT + KEYPAD
Priest will use CTRL + KEYPAD

**Edit
I know it's hard, IsBoxer can be a daunting application with new users, especially with all the different variables to consider. I would HIGHLY recommend watching Mirai's tutorial videos. Yes it will take some time, but you are getting QUALITY with each video. After watching them and understanding IsBoxer more, you will breeze through making a system that works for you.