Not sure, that non-glare screen has been known to cause compatibility issues...
Seriously, I don't know many people hereabouts that multibox it. And as with most "how well will my system run X?" questions, the answer is It Depends(tm). What settings in-game? What else are you running? Are you planning to live-stream or capture? Dual-monitor or internal display only? What OS? Lots of variables, here.
[edit] Only real post so far seems to be this one: http://www.dual-boxing.com/threads/4...A-Realm-Reborn
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