I had a roccat Nyth, which I bought because it was designed for "larger hands." What they did, though was make it for people with *longer fingers.* As someone with wide hands that are normal length, that does me no good. The best mouse I ever had was the Steelseries Cataclysm mouse. Was just wide enough to fit my thumb/pinky grip comfortably and had some really good programmable buttons that weren't all clustered under the thumb. Sadly, those are now extinct.