Think we've all been reported about a bajillion times, especially the PVP guys. I've spoken to a GM about 4 times, mostly with it going like this:

GM: Hey, <character>, you boxing?
Me: Yep.
GM: Sweet! Just confirming you were human. Happy hunting!
Me: o7

I had one GM spam all 5 guys with the same question in about 2 seconds, so their tools apparently use ISBoxer!

I did have one GM mention that she multiboxed 3 characters.

I asked one of them, think it was the last one, to please flag my account as a multiboxer so they could see it easily when investigating mongoloid reports.