If you're high sec mining, you'll want an orca, a freighter, and the rest in barges. Skiffs are the goal; very unlikely to be ganked, and their yield is only beat by the hulk and is the same as a mackinaws. when you mine use a neutral alt in an ibis and shoot at someone to bring concord to the belt. if concord leaves then you know gankers are active in the system and can act accordingly.