For running C5 sites, I highly recommend you upgrade to Proteus instead of the Ishtars. The safety net of the 200k ehp buffer is worth the slight damage loss.
As for capital escalations... Someone will notice what you're doing and put a scan alt(s) into your system, and at some point you will be payed a visit while you're doing sites. It is inevitable. No amount of playing safe can prevent it--Even if you crit every hole into your system before you run sites, and then bubble them. I'm not saying that you won't make money in the meantime, I'm just saying that you have to accept that you will take losses doing escalations.
Soloing C5 sites with 20 characters nets me anywhere from 1-1.5b an hour depending on if someone from my corp made me warpins for the Strongholds and whether or not my three year old is running around

Escalations are better isk/hour, but you're risking significantly more isk on the field to do so. Shrug.
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