Not easily, the first two phases aren't bad, once you get to 25 sanity malady stops bothering you. The major issue is that the adds in p3 bit pretty hard, as a 570 dk I've been below 50% a couple times because the adds get buffed hard. I know that blood Dk's, prot pallies, and hunters can solo, not sure how hard it is as a hunter or pally.
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