There was a informative post on reddit a few days ago which outlines when you should increase the difficulty level while farming.
http://www.reddit.com/r/Diablo/comme...fficulty_math/
While it was written from a solo player perspective, I'd say it probably holds true while multiboxing as well. The OP of the thread does admit to making a mistake, but then links to a different, more accurate, chart (image backup in case the spreadsheet is removed).
Some of you may find this useful.![]()
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